If you’ve been searching for a comforting, crowd-pleasing dish to add to your dinner rotation, look no further than this Creamy Layered John Wayne Casserole Recipe. It’s a delightful combination of hearty seasoned ground beef, a subtly golden biscuit crust, and layers of luscious cheeses and fresh vegetables, all baked to bubbly perfection. Every bite offers a cozy yet exciting mix of textures and flavors that feel like a warm hug on a plate. Whether you’re feeding family or entertaining friends, this casserole is a guaranteed hit that’s simple to prepare and full of personality.

Ingredients You’ll Need
The beauty of this Creamy Layered John Wayne Casserole Recipe lies in its straightforward, pantry-friendly ingredients that come together to create something truly special. Each component plays a crucial role—from the savory seasoned beef to the rich, cheesy layers and vibrant veggies, everything balances perfectly.
- 1 lb ground beef: The hearty base that brings savory richness and protein to the dish.
- 1 packet taco seasoning: Adds a punch of southwestern flavor that spices up the beef beautifully.
- 1/2 cup water: Helps the taco seasoning create a flavorful sauce for the beef.
- 1 can (16.3 oz) refrigerated biscuit dough: Forms a soft, flakey crust that holds all the layers together.
- 1/2 cup sour cream: Provides creamy tanginess that lightens the casserole.
- 1/2 cup mayonnaise: Adds richness and moisture to the cheesy topping.
- 1 cup shredded cheddar cheese (divided): Offers sharp flavor and golden color when melted.
- 1 cup shredded Monterey Jack cheese: Brings a mild, buttery creaminess complementing the cheddar.
- 1 medium onion, sliced: Contributes sweetness and crunch for texture contrast.
- 1 green bell pepper, diced: Adds a fresh, earthy bite and vibrant green color.
- 1 tomato, diced: Infuses juiciness and brightness amidst the cheesy layers.
- 1 can (4 oz) diced green chilies (optional): For a subtle kick of heat and depth.
- Salt and pepper to taste: Essential seasoning to balance and enhance all the flavors.
How to Make Creamy Layered John Wayne Casserole Recipe
Step 1: Prepare the Biscuit Crust
First things first, preheat your oven to 350°F (175°C) and grease a 9×13-inch baking dish. This step ensures the casserole won’t stick and makes cleanup easier. Then, press the refrigerated biscuit dough into the bottom and slightly up the sides of the dish to create that soft, golden crust. Pop it into the oven for about 10 minutes until it’s just lightly golden—this pre-baking step gives the crust structure so it holds all those delicious layers perfectly.
Step 2: Cook the Seasoned Ground Beef
While your crust is baking, brown the ground beef in a skillet over medium heat. Make sure to break it up as it cooks for even texture and flavor. Once the beef is no longer pink, drain any excess grease to avoid sogginess. Then, mix in the taco seasoning and water, letting it simmer until the sauce thickens and clings to every morsel of beef—that’s where the magic flavor happens!
Step 3: Mix the Creamy Cheese Layer
In a small bowl, blend together sour cream, mayonnaise, half the shredded cheddar cheese, and all of the Monterey Jack cheese. This creamy mixture is going to be the luscious layer that ties the casserole together, bringing a dreamy texture and tangy, cheesy flavor you won’t be able to resist.
Step 4: Assemble the Layers
Now comes the fun part—layering! Start by spreading the pre-baked biscuit crust with the seasoned ground beef. Next, scatter the sliced onions, diced green bell pepper, diced tomato, and green chilies if you’re using them. These fresh veggies add wonderful crunch, color, and flavor that balance the richness delightfully.
Step 5: Add the Creamy Topping and Bake
Spread the creamy cheese mixture evenly over your veggie and beef layers, making sure every corner is covered. Then sprinkle the remaining cheddar cheese generously on top. Bake uncovered for 25–30 minutes until the casserole is bubbly and the cheese has turned a gorgeous golden brown. Let it rest for 5–10 minutes before slicing—this gives everything time to set into neat, hearty portions.
How to Serve Creamy Layered John Wayne Casserole Recipe

Garnishes
A sprinkle of freshly chopped cilantro or green onions adds a bright, fresh punch on top, lifting the dish’s flavors beautifully. Don’t shy away from dollops of sour cream or a slice of ripe avocado—these simple garnishes elevate each bite with creamy coolness.
Side Dishes
This casserole shines as a one-dish wonder but pairs wonderfully with crisp garden salads, steamed green beans, or even a side of Spanish rice. These sides add freshness and texture balance, making your meal feel complete and satisfying.
Creative Ways to Present
For a casual family meal, serve it straight from the pan, letting everyone scoop their favorite parts. If hosting guests, consider plating individual slices garnished with avocado slices and a drizzle of salsa for a festive presentation. This Creamy Layered John Wayne Casserole Recipe also works well in smaller ramekins, perfect for personal servings at potlucks or dinners.
Make Ahead and Storage
Storing Leftovers
Once cooled, cover your casserole tightly with foil or plastic wrap and store in the refrigerator. It will keep well for about 3 to 4 days, making it an easy, tasty lunch or dinner for the following days.
Freezing
This dish freezes beautifully! Simply assemble it in a freezer-safe dish before baking and freeze for up to 2 months. When ready to enjoy, thaw it overnight in the fridge and bake as directed, adding extra minutes if needed.
Reheating
Reheat leftover casserole in the oven at 350°F (175°C) for 15-20 minutes or until warmed through and bubbly. You can also microwave individual portions for a quick meal with a little melted cheese goodness restored in no time.
FAQs
Can I substitute the biscuit dough crust?
Absolutely! If you prefer, you can use crushed tortilla chips or make a cornbread crust for a different texture and flavor profile. Just keep in mind the baking times may vary slightly.
What can I use instead of mayonnaise?
If you want a lighter option, Greek yogurt is a great substitute for mayonnaise in the creamy cheese layer, adding tang and moisture without overpowering the other flavors.
Is this casserole spicy?
The level of spice is mild by default, thanks to the taco seasoning and optional green chilies. You can control the heat by choosing mild or hot seasoning packets and adjusting the amount of chilies.
Can I add other vegetables?
Definitely! Corn, black beans, or jalapeños are fantastic additions that complement the existing flavors and textures wonderfully.
How long does it take to prepare and bake?
From start to finish, this Creamy Layered John Wayne Casserole Recipe typically takes about 45 minutes, making it a perfect weeknight meal that feels much more special.
Final Thoughts
If comfort food had a name, it might just be this Creamy Layered John Wayne Casserole Recipe. With its inviting layers of seasoned beef, fresh veggies, and luscious creamy cheese all nestled on a golden biscuit crust, it’s everything you want from a satisfying meal. Give it a try—you’ll find it’s not only easy to make but also a guaranteed crowd-pleaser that you’ll want to come back to again and again.
Print
Creamy Layered John Wayne Casserole Recipe
- Prep Time: 15 minutes
- Cook Time: 30 minutes
- Total Time: 45 minutes
- Yield: 6 servings
- Category: Casserole
- Method: Baking
- Cuisine: Tex-Mex
Description
Creamy Layered John Wayne Casserole is a hearty, cheesy baked dish featuring a biscuit crust layered with seasoned ground beef, fresh vegetables, and a luscious creamy cheese topping. Perfect for a comforting family dinner, this casserole offers bold Tex-Mex flavors with layers of savory beef, tangy sour cream, and melted cheddar and Monterey Jack cheeses.
Ingredients
Crust
- 1 can (16.3 oz) refrigerated biscuit dough
Beef Mixture
- 1 lb ground beef
- 1 packet taco seasoning
- 1/2 cup water
Cheese Mixture
- 1/2 cup sour cream
- 1/2 cup mayonnaise
- 1 cup shredded cheddar cheese, divided
- 1 cup shredded Monterey Jack cheese
Vegetables and Extras
- 1 medium onion, sliced
- 1 green bell pepper, diced
- 1 tomato, diced
- 1 can (4 oz) diced green chilies (optional)
- Salt and pepper to taste
Instructions
- Prepare Oven and Dish: Preheat your oven to 350°F (175°C) and grease a 9×13-inch baking dish to prevent sticking.
- Make Biscuit Crust: Press the biscuit dough evenly into the bottom of the baking dish, extending slightly up the sides to create a crust. Bake this crust for 10 minutes until it turns lightly golden but not fully cooked through.
- Cook Beef Mixture: While the crust bakes, brown the ground beef in a skillet over medium heat. Once cooked, drain the grease, add the taco seasoning and water, then simmer until the mixture thickens, about 5 minutes.
- Mix Creamy Cheese Layer: In a small bowl, combine the sour cream, mayonnaise, half of the shredded cheddar cheese, and all of the Monterey Jack cheese. Stir well and set aside.
- Layer Vegetables and Beef: On top of the pre-baked biscuit crust, spread the seasoned ground beef evenly. Then distribute the sliced onions, diced green bell pepper, diced tomato, and optional diced green chilies evenly over the beef layer.
- Add Creamy Cheese Topping: Spread the prepared creamy cheese mixture over the vegetable and beef layers, making sure to cover everything evenly.
- Top with Cheese: Sprinkle the remaining shredded cheddar cheese over the creamy cheese layer to create a golden, melted topping once baked.
- Bake Casserole: Place the casserole uncovered into the oven and bake for 25 to 30 minutes, until the top is bubbly and golden brown.
- Rest before Serving: Remove the casserole from the oven and let it rest for 5 to 10 minutes. This helps the layers set properly before slicing and serving.
Notes
- Optional diced green chilies add a nice spicy kick but can be omitted for a milder flavor.
- Using refrigerated biscuit dough simplifies the crust preparation and adds a tender base.
- Drain excess grease from the beef to prevent a soggy casserole.
- Let the dish rest before cutting to keep layers intact.
- For a spicier version, add jalapeños or hot sauce to the beef mixture.

