If you have been searching far and wide for a comforting, flavorful, and utterly satisfying dinner, look no further than The Best Meatloaf Recipe. This classic dish hits every note you want from a home-cooked meal—juicy ground beef melded with savory herbs, a perfect balance of spices, and a tangy glaze that caramelizes to perfection as it bakes. Whether you’re cooking for family, friends, or just craving that nostalgic taste of meatloaf, this recipe brings that warmth and heartiness straight to your table with ease and confidence.

Ingredients You’ll Need
Every ingredient in This Best Meatloaf Recipe plays a crucial role, combining simplicity with complexity to create layers of flavor and ideal texture. From the aromatic sautéed onions to the light crunch of Panko breadcrumbs, these essentials come together in a harmonious ensemble.
- 2 lbs ground beef (85% or 80% lean): The hearty base that ensures juicy and tender meatloaf without too much grease.
- 1 medium onion, finely chopped: Adds natural sweetness and depth after being gently sautéed in olive oil.
- 1 tsp olive oil: Helps soften the onions and infuse a subtle fruity flavor.
- 2 large eggs: Bind the ingredients together for a firm yet moist texture.
- 3 garlic cloves, minced: Provide a fragrant, savory kick that’s not overpowering.
- 2 Tbsp ketchup: Adds a touch of sweetness right within the meat mixture.
- 3 Tbsp fresh parsley, finely chopped: Brightens the dish with fresh herbaceous notes.
- 3/4 cup Panko breadcrumbs (or gluten-free breadcrumbs): Keep the meatloaf light by absorbing moisture without getting soggy.
- 1/3 cup milk: Moistens the breadcrumbs for perfect binding.
- 1 tsp salt: Enhances all the natural flavors in the mix.
- 1 tsp Italian seasoning: A blend of herbs that complements the beef beautifully.
- 1/2 tsp ground black pepper: Adds just the right amount of warmth.
- 3/4 cup ketchup (for the sauce): Forms the base of the sticky, tangy glaze topping.
- 1 1/2 tsp white vinegar: Gives a slight tang that balances the sweetness in the glaze.
- 2 Tbsp brown sugar: Caramelizes atop the meatloaf for irresistible flavor and color.
- 1/2 tsp garlic powder: Intensifies the garlicky aroma without overpowering.
- 1/2 tsp onion powder: Adds a gentle umami background.
How to Make The Best Meatloaf Recipe
Step 1: Prepare Your Oven and Baking Sheet
Start by lining a rimmed baking sheet with parchment paper or aluminum foil to make cleanup a breeze. Preheat your oven to 350°F (175°C) so it’s perfectly hot when your meatloaf is ready for the oven. This simple prep sets a great foundation for your cooking.
Step 2: Sauté the Onions
Using about 1 teaspoon of olive oil in a skillet set over medium heat, gently cook your finely chopped onions until they’re soft and golden—this usually takes about 5 to 7 minutes. These caramelized onions add natural sweetness and depth of flavor that will elevate the entire dish. Let them cool before mixing so they don’t warm up the meat prematurely.
Step 3: Mix the Meatloaf Ingredients
In a large bowl, combine your ground beef, cooled sautéed onions, eggs, minced garlic, ketchup, fresh parsley, Panko breadcrumbs soaked in milk, salt, Italian seasoning, and freshly ground black pepper. Use your hands or a sturdy spoon to mix until everything is just combined—try not to overwork it to keep your meatloaf moist and tender.
Step 4: Shape and Bake the Meatloaf
Transfer the mixture onto your prepared baking sheet and gently shape it into a loaf about 8 inches long, 4 inches wide, and 3 inches tall. Bake uncovered for 40 minutes to start setting the shape and letting the flavors meld.
Step 5: Create the Glaze Sauce
While your meatloaf begins baking, mix together the glaze ingredients: ketchup, white vinegar, brown sugar, garlic powder, and onion powder. Stir until smooth and ready to coat your meat masterpiece.
Step 6: Add the Glaze and Finish Baking
After the first 40 minutes, spread the sauce evenly over the meatloaf. Return the pan to the oven for an additional 20 minutes, or until the internal temperature reaches 160°F (71°C). This final stage melts the glaze into a deliciously sticky crust full of tang and sweetness. Rest your meatloaf for 10 to 15 minutes before slicing to ensure juices stay locked in.
How to Serve The Best Meatloaf Recipe

Garnishes
Simple garnishes like fresh parsley or a sprinkle of chopped green onions can add a pop of color and fresh flavor to your plate. Don’t overlook a dollop of creamy mashed potatoes or a side of tangy mustard for dipping—both complement the richness of meatloaf perfectly.
Side Dishes
Classic sides like buttery mashed potatoes, steamed green beans, roasted carrots, or creamy macaroni and cheese pair wonderfully with The Best Meatloaf Recipe. These warm, comforting sides elevate your meal into a full feast that’s sure to satisfy everyone at the table.
Creative Ways to Present
Looking to impress? Slice your meatloaf into thick, hearty portions and serve on a rustic wooden board with small bowls of extra glaze or mustard for dipping. Or, try layering slices inside a soft sandwich bun with lettuce and a slice of cheese for a mouthwatering meatloaf sandwich twist.
Make Ahead and Storage
Storing Leftovers
Once cooled completely, store leftover meatloaf in an airtight container in the refrigerator for up to 4 days. Proper storage maintains the meatloaf’s moisture and flavor so you can enjoy it again without losing any of that homemade goodness.
Freezing
You can freeze cooked meatloaf for up to 3 months by tightly wrapping it in plastic wrap followed by aluminum foil or placing it in a freezer-safe container. Thaw overnight in the refrigerator before reheating to preserve its tender texture and rich flavor.
Reheating
To reheat, cover slices with foil and bake in a preheated 325°F (165°C) oven for about 15-20 minutes or microwave on medium power until warmed through. Reheating gently avoids drying out The Best Meatloaf Recipe and keeps every bite satisfying.
FAQs
Can I use a different type of meat?
Absolutely! While this recipe uses ground beef for richness, you can substitute ground turkey, chicken, or even a mix of pork and beef to suit your taste or dietary needs.
What if I don’t have Panko breadcrumbs?
If you don’t have Panko, regular breadcrumbs or crushed crackers or oats can work too. Just be mindful they may affect the texture slightly but will still help bind and add moisture.
Is it necessary to sauté the onions first?
While not strictly required, sautéing the onions enhances their sweetness and softness, contributing significantly to the flavor and texture of the meatloaf.
Can I make this recipe gluten-free?
Yes! Just swap out the Panko breadcrumbs for a gluten-free variety, and double-check any seasoning or condiment labels to keep it gluten-free-friendly.
How do I know when the meatloaf is fully cooked?
The safest way is to use a meat thermometer—The Best Meatloaf Recipe should reach an internal temperature of 160°F (71°C) to ensure it’s cooked through and safe to eat.
Final Thoughts
There’s something incredibly comforting about The Best Meatloaf Recipe, with its perfect blend of savory, sweet, and herbaceous flavors wrapped in a tender, juicy package. Whether you’re new to meatloaf or revisiting a beloved classic, this recipe invites you to experience the warmth and satisfaction that only a truly impeccable meatloaf can bring. Give it a try—you’ll be making it again and again in no time!
Print
The Best Meatloaf Recipe
- Prep Time: 15 minutes
- Cook Time: 1 hour
- Total Time: 1 hour 15 minutes
- Yield: 6 servings
- Category: Main Course
- Method: Baking
- Cuisine: American
Description
This classic meatloaf recipe delivers a moist and flavorful dish perfect for family dinners. Ground beef is combined with sautéed onions, herbs, and breadcrumbs, baked to perfection, then topped with a tangy, sweet ketchup glaze for a comforting and hearty meal.
Ingredients
Meatloaf
- 2 lbs ground beef (85% or 80% lean)
- 1 medium onion, finely chopped
- 1 tsp olive oil
- 2 large eggs
- 3 garlic cloves, minced
- 2 Tbsp ketchup
- 3 Tbsp fresh parsley, finely chopped
- 3/4 cup Panko breadcrumbs (or gluten-free breadcrumbs)
- 1/3 cup milk
- 1 tsp salt
- 1 tsp Italian seasoning
- 1/2 tsp ground black pepper
Glaze Sauce
- 3/4 cup ketchup
- 1 1/2 tsp white vinegar
- 2 Tbsp brown sugar
- 1/2 tsp garlic powder
- 1/2 tsp onion powder
Instructions
- Prep: Line a rimmed baking sheet with parchment paper or foil and preheat the oven to 350°F (175°C).
- Sauté the Onions: Heat a medium skillet over medium heat and add 1 tsp olive oil and the chopped onion. Sauté, stirring occasionally, until the onion softens and becomes golden, about 5-7 minutes. Transfer to a plate and allow to cool.
- Make the Meatloaf Mixture: In a large bowl, combine the ground beef, sautéed onions, eggs, minced garlic, ketchup, fresh parsley, Panko breadcrumbs, milk, salt, Italian seasoning, and black pepper. Mix thoroughly but avoid overmixing to keep the meatloaf tender.
- Shape the Meatloaf and Bake: Transfer the meat mixture to the prepared baking sheet and shape it into a loaf about 8 inches long, 4 inches wide, and 3 inches tall. Bake uncovered at 350°F (175°C) for 40 minutes.
- Make the Sauce: In a small bowl, combine the ketchup, white vinegar, brown sugar, garlic powder, and onion powder. Stir until smooth to create the glaze.
- Add the Glaze: Remove the meatloaf from the oven after 40 minutes. Spread the sauce evenly over the top, then return it to the oven. Bake for an additional 20 minutes, or until the internal temperature reaches 160°F (71°C).
- Rest and Serve: Remove the meatloaf from the oven and let it rest for 10-15 minutes to allow juices to redistribute before slicing and serving.
Notes
- Use Panko breadcrumbs for a lighter texture; gluten-free breadcrumbs work well as a substitute.
- Allowing the meatloaf to rest after baking ensures juicier slices.
- Check the internal temperature with a meat thermometer to ensure it’s safely cooked.
- Leftovers can be stored in the refrigerator for up to 3 days or frozen for longer storage.
- Feel free to add your favorite herbs or a splash of Worcestershire sauce for a flavor twist.

